Emerging evidence from observational studies has suggested that metformin may be beneficial in the primary prevention of colorectal cancer (CRC). Multivariable logistic regressions were used to estimate the association between obesity status and infectious, wound, and perfusion complications within one year of surgery. Objective: To study the trends on JMG using Truven Health MarketScan commercial claims database. Author information: (1)Eli Lilly and Company, Indianapolis, IN, USA. Having a large cohort of identified pregnancy exposures may facilitate the assessment of individual and often rare congenital abnormalities. This database contains deidentified information on geographically diverse, commercially insured patients in the United States. Background: There are limited published studies on JMG on incidence, prevalence, morbidity, mortality, investigations and therapeutic strategies in using insurance claims database. This study evaluated the real-world practice patterns in gout patients using large administrative claims databases. Each includes data on enrollment, inpatient and outpatient medical claims, and outpatient pharmacy claims for a convenience sample of enrollees and their dependents with either private insurance (through their employers or a health plan) or … In addition, the prescription database lacks information on medication dispensed during hospital admissions or obtained from the doctor's office as samples. Maternal depressive symptoms were associated with greater odds of ED expenditures [odds ratio (OR) 1.26; 95 % CI 1.03-1.54] and lesser odds of dental expenditures (OR 0.81; 95 % CI 0.66-0.98) and total expenditures (OR 0.71; 95 % CI 0.51-0.98). Working off-campus? The findings of the claims analysis were then compared with the results of the final analysis of the registry. Truven MarketScan (2009 through 2018) Commercial and Medicare Advantage data from ~140 million employees and dependents covered by the health benefit programs of large employers. New HTN patients with ≥2 rounds of treatment options (vs single/initial round) were associated with ∼5-fold or higher predicted HTN complications’ risk (p-value < 0.0001). The University of North Carolina Chapel Hill, through The North Carolina Translational and Clinical Sciences Institute (NC TraCS), holds an annually renewable license for the IBM® MarketScan® Commercial Claims and Encounters and Medicare Supplemental Databases for the years 2000 through 2018. Truven Health Analytics is an IBM Watson Health Company that provides healthcare data and analytics services. Conclusions: The total cost for outpatient GI endoscopy examinations was $32.4 billion. Possible reasons for patients not receiving 2 L treatment include still being on 1 L treatment, no requirement for 2 L treatment, refusal of treatment and death, although these cannot be reliably obtained from the claims database These differences should be taken into account when comparing the IRs of AEs between the cohorts. New (n = 200,786) or all (n = 4.1 million) HTN patients were identified from 2015, 2016 enrollments in a nationwide administrative claims’ database and compared for HTN-specific treatment (Rx) choices, Rx count, and distinct rounds o f treatment o ptions ( ROTO ), respectively. The Truven Database was queried for subjects that underwent meniscus allograft transplantation (Current Procedural Terminology code 29868) in the outpatient setting with minimal 2-year follow-up. IRs were identified based on the occurrence of outpatient treatment, emergency room (ER) visit, and/or hospitalization for hypersensitivity and allergic reactions. In particular, key challenges relate to the identification of pregnancy episodes, determination of gestational age, the linkage of mothers and infants, ascertainment of exposures and outcomes, and the careful interpretation of results in light of study and data limitations. International Journal of Medical Informatics. Database Name: MarketScan® Commercial Claims and Encounters and Medicare Supplemental and Coordination of Benefits. Design, Setting, and Participants Reoperation was defined by ipsilateral knee procedure after the index … Objective: Consistent with many pregnancy exposure registries, pregnant women in the sumatriptan, naratriptan, and sumatriptan/naproxen sodium registry could be enrolled at any time during the course of the pregnancy, whereas follow‐up for outcomes in the claims analysis began at the earliest date of triptan exposure as determined by filled prescriptions. During the 12‐month period prior to the pregnancy episode, 25.7% of sumatriptan‐exposed women had dispensing of nonsteroidal anti‐inflammatory agents while 49.2% had dispensing of opioids. About 4519 pregnancies were exposed to sumatriptan, 230 were exposed to naratriptan, and 371 were exposed to sumatriptan/naproxen sodium. Gender and ethnicity distributions were similar between the NAMCS and the CEMR. Truven Health Analytics MarketScan Databases for Clinical Research in Colon and Rectal Surgery Clin Colon Rectal Surg . Truven MarketScan. Around 75% of migraine patients are women, and the prevalence of migraine is the highest for ages 20 to 50 years, when women are of reproductive age.7 Pharmacologic treatment of migraine during pregnancy is typically focused on acute medications, and sporadic use of triptans after the first trimester may be considered. Methods: Approximately 60% of the study participants were male and 40% were female in each group. This criterion would exclude infants that die during the first year of life (perhaps due to serious congenital malformations or other causes). Predictor variables included age, timing of reconstruction, body mass index, history of radiation therapy, history of venous … The incidence of IRs requiring medical intervention was 8.4%. This study aimed to assess the generalizability and representativity of the widely used US Centricity Electronic Medical Record (CEMR), a primary and ambulatory care EMR for population health research, using data from the National Ambulatory Medical Care Surveys (NAMCS) and the National Health and Nutrition Examination Surveys (NHANES). Methods: Penn State Hershey Medical Center and Penn State College of Medicine, Management of Gout in the United States: A Claims‐based Analysis, Big Data in Cancer Research: Real-World Resources for Precision Oncology to Improve Cancer Care Delivery. It contains complete information on inpatient prescriptions, as well as links to outpatient prescription data. After adjusting for health care use, the beneficial effect of metformin was reduced to 12% (AOR, 0.88; 95% confidence interval, 0.77-1.00 [P = .05]). Of 25 481 patients who underwent colectomy, 4160 were included in the study. METHODS: Adult patients who received EGFR-inhibitor treatment between 2004 and 2015 after a diagnosis of colon, head and neck, lung, breast, or thyroid cancer were identified. Although treatment patterns’ analyses at scale can provide insights into associated health outcomes, they remain relatively uncharacterized for most chronic diseases, including hypertension (HTN). AU - Hollenbeak, Christopher S. PY - 2019. Methods: Marketscan® Commercial Claims and Encounters and Medicare Supplemental Databases. Triptan exposure in pregnant migraine patients therefore offers a good example to examine whether assessment of safety using existing databases can provide findings comparable to those from a prospective pregnancy registry. Details on patients with CRC receiving cetuximab in 2004-2006 were extracted from a large USA administrative claims database. Physician-graded toxicity is a relatively more objective measure, but relies on both clinicians fully assessing all relevant symptoms and patients accurately reporting them to the clinician. Metformin use appears to be associated with a reduced risk of developing CRC among diabetic patients in the United States. Specifically, we discuss six main endophenotype hypotheses in AD: amyloidosis, tauopathy, neuroinflammation, mitochondrial dysfunction, vascular dysfunction, and lysosomal dysfunction. No differences were found regarding perception of symptom seriousness and symptom disclosure between age groups as no longer duration to diagnosis or treatment was observed in the oldest groups. For 2016, ACE inhibitors/ARBs were most frequent choices in new HTN patients’ vs more diverse Rx-choices among all HTN patients. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Among both commercially insured and Medicaid-insured women, the likelihood of having HS vs LS increased over time. The findings of this study support an approach of using existing health care database (s) in the post‐approval assessment of medication exposure in pregnancy. Inclusion in the study required the patient to have an International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis code for ulcerative colitis. ∼95% of new HTN patients in 2016 did not start treatment with current literature-recommended first option, Thiazides. Similarly, the proportion of outcomes that were elective abortions, spontaneous abortions, and livebirths for first‐trimester naratriptan exposures in the registry were 1.9%, 9.6%, and 88.5%, respectively, and similar to the claims analysis, there were no recorded stillbirths. While there is evidence in the claims of patients receiving a prescription dispensing at an outpatient pharmacy, we are unable to verify that patients used the medication. Trends in the percentage of patients with prescription claims for generic and branded warfarin were compared by year and 6-month periods using chi-square tests and generalized linear models adjusting for patient characteristics. The study population for the claims analysis was drawn from administrative claims data contained in the Truven Health Marketscan Commercial Claims and Encounters and Medicare Supplemental and Coordination of Benefits Databases for the period of 1996 to 2012. These data were obtained from the National Ambulatory Medical Care Survey; National Health and Wellness Survey; Nationwide Inpatient Sample; Surveillance, Epidemiology, and End Results Program; National Vital Statistics System; Thompson Reuters MarketScan; Medicare; Medicaid; and the Clinical Outcomes Research Initiative's National Endoscopic Database. Of the 2476 patients identified, 1379 (55.7%) were men, and the mean (SD) age was 42.1 (12.9) years. Its brands include 100 Top Hospitals, Action OI, Advantage Suite, CareDiscovery, MarketScan, Micromedex, and Simpler. The Truven Health MarketScan Commercial Claims and Encounter Database and the Medicare Supplemental and Coordination of Benefits Database (Truven Health Analytics Inc, Ann Arbor, MI) included data from January 1, 2007, to September 30, 2015. The MarketScan Commercial Claims and Encounters Database is a research database owned by Truven Health Analytics. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. It is possible that cancer in the elderly is being managed or treated differently than in their younger counterparts. BACKGROUND Learn more. IBM MarketScan Research Databases at UCSF (formerly Truven Health Analytics Inc.) Data Description . Costs were determined from paid claims and QALY utilities were obtained from the literature. 2. The objectives of this study were to compare, by patient obesity status, the contemporary utilization patterns of different reconstruction surgery types, understand postoperative complication profiles in the community setting, and analyze the financial impact on health care payers and patients. Studies. Health Research Data for the Real World: The MarketScan In this analysis, we sought to assess outcomes associated with exposure of 3 triptan products in pregnancy using an existing health care database and compare the key findings with that of a previously completed pregnancy exposure registry.8. Market Scan combines science, technology and data to provide industry leading solutions that enable OEMs and lenders to maximize their market penetration through analytics, and empower dealers to achieve digital retailing supremacy. Marketscan® File Structure. Our study demonstrates the power of EHRs for clinical description of CF and the benefits of using a genetics-informed weighing scheme in construction of a phenotype risk score. Band Today is based on national attrition levels in Truven database Analytics, artificial intelligence, visualization... Help clinicians become more informed readers of the largest proprietary collections of de-identified US patient available... 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